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Cards (14)

  • the AST assay is a continuous monitoring or kinetic assay
  • alanine aminotransferase is ALT
  • alkaline phosphatase is also called ALP or ALKP
  • osteoblasts use alkaline pH to deposit calcium phosphate on bone
  • calcium will be taken from bones to keep calcium plasma at normal levels, needed for blood clotting, neuron function, muscle function
  • isoenzyme of alkaline phosphatase exist based on location of alkaline phosphatase (meaning alkaline phosphatase of liver will be an isoenzyme of alkaline phosphatase found in intestines); isoenzyme test is rarely orderd
  • when isoenzyme test for alkaline phosphatase is ordered, usually a bone disorder is suspected; differentiation was done via electrophoresis, but is not done via immunoassay
  • alkaline phosphatase assay is kinetic
  • acid phosphatase Assay - acid version of ALP; acid buffer instead of alkaline buffer endpoint assay; same reagent
  • Gamma-glutamyltransferase (GGT)'s Exact physiological function is unknown 
  • GGT is a transferase
  • coumadin [anticoagulant], phenolbarb, dilantin [both antiseizure meds]
  • GGT isn't used in routine evaluations of liver disorders
  • GGT assay is an endpoint or kinetic assay