exam 2 final final review

• dye binding

  Methyl orange - disadvantage being it does not bind to all proteins
• HABA disadvantages

  many interferences: aspirin, penicillin, conjugated bilirubin, and sulfonamides (4)
• BCG disadvantages

  • bilirubin interferes
  • low albumin levels can be overestimated (can look lower than they actually are) 
  • after five minutes, a-1 globulins may start to absorb dye
• BCP advantage - more specific for albumin
• BCP disadvantages

  • in some renal patients, albumin can be structurally altered and BCP will not always bind to that albumin
• SPEP findings

  • Viral hepatitis
  • Decrease in a-1, a-2, and beta (3)
  • Marked decrease in albumin
  • Increase in gamma