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Topic 2: Genes and Health
2.1 The Structure of DNA and RNA
2.1.1 Nucleotides
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What does DNA stand for?
Deoxyribonucleic Acid
DNA stores the genetic information of an
organism
RNA is typically
single-stranded
.
Match the sugar molecule with the correct nucleic acid:
Deoxyribose ↔️ DNA
Ribose ↔️ RNA
What type of bond connects nucleotides in a nucleic acid chain?
Phosphodiester bond
The nitrogenous bases in DNA are A, G, C, and
T
Match the nucleotide component with its function:
Pentose Sugar ↔️ Forms the backbone
Phosphate Group ↔️ Connects nucleotides
Nitrogenous Base ↔️ Carries the genetic code
What is the primary role of DNA?
Stores genetic information
DNA has a double-stranded helix structure, while RNA is typically
single-stranded
RNA contains the sugar deoxyribose.
False
Which nitrogenous base is found in RNA but not in DNA?
Uracil
The chemical formula for DNA is
(
C
5
H
10
O
4
)
n
(C_{5}H_{10}O_{4})_{n}
(
C
5
H
10
O
4
)
n
, while for RNA it is (C_{5}H_{10}O_{5})_{n}</latex>, highlighting the difference in their sugars
The chemical formula for DNA is
(C_{5}H_{10}O_{4})_{n}
What is the primary role of DNA?
Stores genetic information
DNA is a double-stranded
helix
RNA is typically a double-stranded structure.
False
What sugar is found in RNA?
Ribose
The nitrogenous base unique to RNA is
uracil
What are the three key components of a nucleotide?
Pentose sugar, phosphate group, nitrogenous base
In DNA, the pentose sugar is
deoxyribose
What type of bonds connect nucleotides in a nucleic acid chain?
Phosphodiester bonds
Purines have a single-ring structure.
False
DNA contains deoxyribose sugar, while RNA contains
ribose
Which nitrogenous base is used in DNA but not in RNA?
Thymine
DNA strands exhibit polarity with a 5' phosphate end and a
3'
hydroxyl end.
Steps in the formation of DNA or RNA strands
1️⃣ Phosphodiester bonds form between nucleotides
2️⃣ Water molecule is removed
3️⃣ Linear chain of nucleotides forms
What is the structure of DNA?
Double-stranded helix
RNA is typically a single-stranded
molecule
What is the role of RNA in protein synthesis?
Participates in various steps
The chemical formula for RNA is (C5H10O4)n.
False
What is the pentose sugar in DNA?
Deoxyribose
To which carbon of the pentose sugar is the phosphate group attached?
5'
The nitrogenous base in a nucleotide is attached to the
1'
carbon of the sugar.
Match the component with its function:
Pentose Sugar ↔️ Forms the backbone
Phosphate Group ↔️ Connects nucleotides
Nitrogenous Base ↔️ Carries the genetic code
The second carbon in ribose has an oxygen atom, while
deoxyribose
does not.
What are the two key differences between DNA and RNA nucleotides?
Pentose sugar and bases
DNA contains deoxyribose, which has one less
oxygen
atom compared to ribose in RNA.
DNA uses thymine (T), while RNA uses
uracil
(U).
Steps in the formation of DNA or RNA strands
1️⃣ 5' phosphate group bonds to 3' hydroxyl group
2️⃣ Water molecule is removed
3️⃣ Phosphodiester bond is formed
4️⃣ Linear chain with polarity is created
What is the primary function of DNA in genetic information?
Genetic storage
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