6.3.1 Amines

• Amines are structurally similar to ammonia but have hydrogen atoms replaced by alkyl or aryl groups.


  True
• What type of substituents are found in amines?

  Alkyl or aryl groups
• The number of substituents on the nitrogen atom in amines affects their chemical properties.


  True
• Match the type of amine with its definition:

  Primary Amine ↔️ One alkyl or aryl group attached to nitrogen

  Secondary Amine ↔️ Two alkyl or aryl groups attached to nitrogen

  Tertiary Amine ↔️ Three alkyl or aryl groups attached to nitrogen
• What is an example of a secondary amine according to its nomenclature?

  Dimethylamine
• Steps to name the tertiary amine `(CH3)3-N`

  1️⃣ Identify it as a tertiary amine

  2️⃣ Name the three methyl groups

  3️⃣ Add "amine" to the end

  4️⃣ The name is Trimethylamine
• Boiling points of amines are higher than alkanes but lower than alcohols.


  True
• Match the amine type with its naming convention:

  Primary Amine ↔️ Name the alkyl group followed by "amine"

  Secondary Amine ↔️ Name the two alkyl groups prefixed by "N-" followed by "amine"

  Tertiary Amine ↔️ Name the three alkyl groups prefixed by "N-" followed by "amine"
• Amines are soluble in water if they have small alkyl groups

  True
• Most amines have a characteristic ammonia-like odor
• The lone pair of electrons on the nitrogen atom makes amines nucleophilic, allowing them to participate in substitution reactions
• Many drugs contain amine groups for their biological activity
• Order the applications of amines based on their primary benefits:

  1️⃣ Pharmaceuticals for biological activity

  2️⃣ Dyes for vibrant colors

  3️⃣ Cosmetics for stability and color

  4️⃣ Plastics for strength and durability

  5️⃣ Agricultural Chemicals for crop protection
• What is the key structural feature of amines?

  Nitrogen atom with lone pair
• The general formula for a primary amine is R-NH2
• A primary amine has one alkyl or aryl group attached to the nitrogen
• What is an example of a primary amine?

  Methylamine
• The naming convention for primary amines involves naming the alkyl or aryl group followed by the word amine
• To name a tertiary amine, you name all three alkyl or aryl groups and add "amine" at the end.


  True
• What is the characteristic odor of most amines?

  Ammonia-like
• Amines are soluble in water if they have small alkyl groups.
• The nitrogen atom in an amine has a lone pair of electrons
• Amines are classified based on the number of alkyl or aryl groups attached to the nitrogen atom


  True
• The number of substituents in an amine affects its reactivity and physical properties


  True
• For mixed substituents in naming amines, they should be listed alphabetically
• The boiling points of amines are higher than alkanes but lower than alcohols
• Amines are basic compounds due to the lone pair of electrons on the nitrogen atom


  True
• Match the property of amines with its explanation:

  Basicity ↔️ Lone pair of electrons on nitrogen

  Nucleophilicity ↔️ Lone pair allows substitution reactions

  Reactivity with Acids ↔️ Forms ammonium salts
• Amines are used in cosmetics to add stability and color


  True