lipid metabolism

Created by

kiah

Cards (29)

most abundant type of lipids 
triglycerides
lipid formed by esterification of?
3 fatty acids to 1 glycerol -> triester +3 h2o
the location of triacylglycerides
adipocytes
simple  
identical fas
mixed 
more than 1 fas
what happened in churning action?
produce small fat droplets (chyme)
hydrolyze 10% TAGs to monoglycerols
gastric lipase
solubilizes droplets
bile
pancreatic lipase 
produce monoglycerols which from fatty acid and micelles, it hydrolyze ester linkages
in intestinal walls, the micelles repackaged into TAGs to form chylomicron
intestinal lacteals are lymphatic vessels that are found underneath your intestinal cells
imported TAGs form droplet in the periphery, merge into the large central fat globule
mobilization is the hydrolysis of TAGs to became free fatty acid in the bloodstream
the mobilization is influenced by glucagon and epinephrine
the enzyme required in the mobilization if hormone sensitive lipase
how many molecules is being released everytime there is a complete hydrolysis of TAG molecule? 
1
where will the TAGs go once they are in the bloodstream? 
kidney of liver and is converted to DHAP
glycerol become glycerol-3-hosphate by the enzyme: glycerol kinase
glucose-3-phosphate will become DHAP by the enzyme Glycerol-3-phosphate dehydrogenase
fatty acid activation site in outer mitochondrial membrane
in fatty acid activation, the 2 high energy phosphate bonds expended
in fatty acid activation, fas are converted into high energy derivative of coenzyme a
carnitine is used as shuttle
acyl coa will be transferred in carnitine by carnitine palmitoyl transferase. it is the RLE
fatty acyl carnitine shuttled through the membrane by translocase
fatty acid B-oxidation is the reaction sequence repeatedly 2Cs at a time from -COOH end of the acyl CoA molecule
the site of beta oxidation is in the mitochondrial matrix
the carrier for intermediates in beta oxidation if Coenzyme A
the oxidizing reagent in beta oxidation is FAD and NAD